Docking of human rhodopsin mutant (Gly90àAsp) with beta-arrestin and cyanidin 3-rutinoside to cure night blindness
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منابع مشابه
Docking of human rhodopsin mutant (Gly90→Asp) with beta-arrestin and cyanidin 3-rutinoside to cure night blindness
MOTIVATION Rhodopsin is a visual pigment present in rod cells of retina. It belongs to GPCR family and involves photoisomerization of 11-cis-retinal to all-trans-retinal isomers, conformational changes in rhodopsin and signal transduction cascade to generate a nerve impulse. This signaling pathway has been targeted to eliminate the effect of a mutation (Gly90→Asp) responsible for abnormal activ...
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ژورنال
عنوان ژورنال: Bioinformation
سال: 2012
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630008128